Free tool
Can I eat this with Duloxetine?
Alcohol may increase liver injury risk, and St John's wort should not be used with duloxetine.
Also sold as Cymbalta, Depalta, Duciltia, Dutor, Yentreve. Brand names from the NHS Dictionary of Medicines and Devices.
Type any food below for an instant verdict — we check 34 foods and drinks for Duloxetine (5 to avoid, 28 to take care with) — or tap one below.
Quick answers
- Should I take Duloxetine with food?
- You can take duloxetine once or twice day, with or without food.
- Can I eat st john’s wort with Duloxetine?
- No, avoid it. Do not use St John's wort when taking duloxetine.
- Can I drink alcohol with Duloxetine?
- Yes, with care. Best avoided as it can increase the risk of side effects and may be associated with severe liver injury.
Grounded in the checker below. Not a substitute for your pharmacist.
1 · What do you take?
Alcohol may increase liver injury risk, and St John's wort should not be used with duloxetine.
You can eat normally while taking duloxetine. It's best not to drink alcohol as it can increase the risk of side effects and may be associated with severe liver injury. Do not use St John's wort. Duloxetine can be taken with or without food.
Browse our medication food guides →2 · What do you want to eat or drink?
When to take it: You can take duloxetine once or twice day, with or without food.
Tap a food to see the answer, or type any food or drink in the box above.
Foods to avoid with Duloxetine· 5
Take care with Duloxetine· 28
Fine with Duloxetine· 1
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This checker summarises published guidance (NHS medicine pages, patient information leaflets and drug labels) for general information only. It is not medical advice, it is not exhaustive, and it cannot account for your dose, kidney function, other medicines, or health conditions. Always follow your prescriber, pharmacist, or the patient information leaflet — especially before changing what you eat or drink. See our editorial policy.
Further reading on Duloxetine
The pages our answers quote. Every answer shows “Where this comes from” with the exact words, checked 24 September 2026. How we check
The Journal
Read our medication food guides →
A full Duloxetine guide is on its way. Meanwhile, the Journal covers timing, grapefruit, alcohol and more.
Food groups that matter with Duloxetine
Every medicine each one affects, on one page.
Medicines with similar food rules
Affected by the same foods as Duloxetine.