Free tool
Can I eat this with Isotretinoin?
Isotretinoin must be taken with food to absorb properly, and alcohol should be avoided because it could cause liver problems.
Type any food below for an instant verdict — we check 29 foods and drinks for Isotretinoin (27 to avoid, 1 to take care with) — or tap one below.
Quick answers
- Can I drink alcohol with Isotretinoin?
- No, avoid it. Do not drink alcohol while taking isotretinoin as it could cause liver problems.
- Can I eat vitamin a supplements with Isotretinoin?
- No, avoid it. Do not take vitamin A supplements as they may not mix well with isotretinoin.
- Can I eat liver with Isotretinoin?
- Yes, with care. Liver is very high in vitamin A; avoid it as extra vitamin A can be harmful with isotretinoin.
Grounded in the checker below. Not a substitute for your pharmacist.
1 · What do you take?
Isotretinoin must be taken with food to absorb properly, and alcohol should be avoided because it could cause liver problems.
Take isotretinoin with a meal – food more than doubles how much your body absorbs. Avoid alcohol as it could harm your liver. Do not take vitamin A supplements or eat liver, as too much vitamin A can be harmful. Avoid soya if you have a peanut or soya allergy.
Browse our medication food guides →2 · What do you want to eat or drink?
Tap a food to see the answer, or type any food or drink in the box above.
Foods to avoid with Isotretinoin· 27
Take care with Isotretinoin· 1
Fine with Isotretinoin· 1
Get the full Isotretinoin (Roaccutane) food guide by email
The complete Isotretinoin (Roaccutane) list — safe swaps, portion notes, and the freshness rules that matter — plus first access to the FreshPlate app, which checks every recipe against your medications automatically.
Free forever. Unsubscribe any time.
This checker summarises published guidance (NHS medicine pages, patient information leaflets and drug labels) for general information only. It is not medical advice, it is not exhaustive, and it cannot account for your dose, kidney function, other medicines, or health conditions. Always follow your prescriber, pharmacist, or the patient information leaflet — especially before changing what you eat or drink. See our editorial policy.
Further reading on Isotretinoin
The pages our answers quote. Every answer shows “Where this comes from” with the exact words, checked 24 September 2026. How we check
NHS website
Isotretinoin: a medicine for severe acne
NHS information about the medicine isotretinoin, including what it's used for, who can use it, how to use it and side effects.
US FDA drug label
US FDA drug label: Isotretinoin
The official US prescribing information for Isotretinoin, including how food, drink and other medicines affect it.
The Journal
Read our medication food guides →
A full Isotretinoin guide is on its way. Meanwhile, the Journal covers timing, grapefruit, alcohol and more.
Food groups that matter with Isotretinoin
Every medicine each one affects, on one page.