Free tool
Can I eat this with Oxycodone?
Grapefruit juice and alcohol interact with oxycodone; food changes absorption slightly; some foods may help manage common side effects like constipation.
Also sold as Abtard, Candox, Carexil, Dolocodon PR, Ixyldone, Leveraxo, Longtec, Lynlor, Onexila XL, Oxeltra, Oxyact, OxyContin and 7 more. Brand names from the NHS Dictionary of Medicines and Devices.
Type any food below for an instant verdict — we check 48 foods and drinks for Oxycodone (11 to avoid, 29 to take care with) — or tap one below.
Quick answers
- Should I take Oxycodone with food?
- You can take it with or without food.
- Can I drink grapefruit juice with Oxycodone?
- No, avoid it. Do not drink it while taking oxycodone.
- Can I eat grapefruit with Oxycodone?
- No, avoid it. Do not drink grapefruit juice while taking oxycodone.
- Can I drink alcohol with Oxycodone?
- Yes, with care. It can make you sleepy and increase the risk of serious side effects.
Grounded in the checker below. Not a substitute for your pharmacist.
1 · What do you take?
Grapefruit juice and alcohol interact with oxycodone; food changes absorption slightly; some foods may help manage common side effects like constipation.
Do not drink grapefruit juice while taking oxycodone. Avoid alcohol as it can make you feel sleepy and increase the risk of serious side effects. You can take oxycodone with or without food, though a high-fat meal increases absorption by about 27%.
Browse our medication food guides →2 · What do you want to eat or drink?
When to take it: You can take it with or without food.
Tap a food to see the answer, or type any food or drink in the box above.
Foods to avoid with Oxycodone· 11
Take care with Oxycodone· 29
Fine with Oxycodone· 8
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This checker summarises published guidance (NHS medicine pages, patient information leaflets and drug labels) for general information only. It is not medical advice, it is not exhaustive, and it cannot account for your dose, kidney function, other medicines, or health conditions. Always follow your prescriber, pharmacist, or the patient information leaflet — especially before changing what you eat or drink. See our editorial policy.
Further reading on Oxycodone
The pages our answers quote. Every answer shows “Where this comes from” with the exact words, checked 24 September 2026. How we check
NHS website
Oxycodone: a medicine for severe pain
NHS information about the medicine oxycodone, including what it's used for, who can take it, how to take it and side effects.
US FDA drug label
US FDA drug label: Oxycodone
The official US prescribing information for Oxycodone, including how food, drink and other medicines affect it.
The Journal
Read our medication food guides →
A full Oxycodone guide is on its way. Meanwhile, the Journal covers timing, grapefruit, alcohol and more.
Food groups that matter with Oxycodone
Every medicine each one affects, on one page.
Medicines with similar food rules
Affected by the same foods as Oxycodone.