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Can I eat this with Promethazine?
Promethazine makes you drowsy, and alcohol makes this much worse. It can also make side effects like dry mouth worse.
Also sold as Avomine, Phenergan Nightime, Sominex, Vertigon. Brand names from the NHS Dictionary of Medicines and Devices.
Type any food below for an instant verdict — we check 30 foods and drinks for Promethazine (29 to avoid, 0 to take care with) — or tap one below.
Quick answers
- Should I take Promethazine with food?
- You can take promethazine with or without food.
- Can I drink alcohol with Promethazine?
- No, avoid it. Do not drink alcohol. It can make you sleep very deeply so you cannot breathe properly and may not wake up.
Grounded in the checker below. Not a substitute for your pharmacist.
1 · What do you take?
Promethazine makes you drowsy, and alcohol makes this much worse. It can also make side effects like dry mouth worse.
Do not drink alcohol with promethazine as it can make you sleep very deeply and affect your breathing. You can eat normally while taking promethazine. The medicine can be taken with or without food.
Browse our medication food guides →2 · What do you want to eat or drink?
When to take it: You can take promethazine with or without food.
Tap a food to see the answer, or type any food or drink in the box above.
Foods to avoid with Promethazine· 29
Fine with Promethazine· 1
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This checker summarises published guidance (NHS medicine pages, patient information leaflets and drug labels) for general information only. It is not medical advice, it is not exhaustive, and it cannot account for your dose, kidney function, other medicines, or health conditions. Always follow your prescriber, pharmacist, or the patient information leaflet — especially before changing what you eat or drink. See our editorial policy.
Further reading on Promethazine
The pages our answers quote. Every answer shows “Where this comes from” with the exact words, checked 24 September 2026. How we check
NHS website
About promethazine
NHS medicines information on promethazine – what it's used for and key facts.
NHS website
Who can and cannot take promethazine
NHS medicines information on who can take promethazine and who may not be able to take it.
NHS website
How and when to take promethazine
NHS medicines information on dosage for promethazine, how to take it and what to do if you miss a dose or take too much.
NHS website
Side effects of promethazine
NHS medicines information on side effects of promethazine and what you can do to cope.
NHS website
Taking promethazine with other medicines and herbal supplements
NHS medicines information on possible interactions with promethazine and other medicines, herbal remedies and supplements.
The Journal
Read our medication food guides →
A full Promethazine guide is on its way. Meanwhile, the Journal covers timing, grapefruit, alcohol and more.
Food groups that matter with Promethazine
Every medicine each one affects, on one page.