Free tool
Can I eat this with Trimethoprim?
You can take trimethoprim with or without food. If you feel sick, taking it with food may help. Avoid rich or spicy food if you have nausea or vomiting.
Also sold as Monotrim, Trimogal, Trimopan. Brand names from the NHS Dictionary of Medicines and Devices.
Type any food below for an instant verdict — we check 40 foods and drinks for Trimethoprim (0 to avoid, 37 to take care with) — or tap one below.
Quick answers
- Should I take Trimethoprim with food?
- You can take trimethoprim with or without food.
- Can I eat rich food with Trimethoprim?
- Yes, with care. Stick to simple meals and avoid rich food while you're taking this medicine if you feel sick.
- Can I eat spicy food with Trimethoprim?
- Yes, with care. Stick to simple meals and avoid spicy food while you're taking this medicine if you feel sick.
- Can I drink alcohol with Trimethoprim?
- Yes, with care. It's best not to drink too much alcohol if you have headaches while taking trimethoprim.
Grounded in the checker below. Not a substitute for your pharmacist.
1 · What do you take?
You can take trimethoprim with or without food. If you feel sick, taking it with food may help. Avoid rich or spicy food if you have nausea or vomiting.
Trimethoprim can be taken with or without food. If it makes you feel sick, try taking it with or after a meal and stick to simple meals. Avoid rich or spicy food while taking this medicine. There are no specific food or drink restrictions, and you can eat and drink normally.
Browse our medication food guides →2 · What do you want to eat or drink?
When to take it: You can take trimethoprim with or without food.
Tap a food to see the answer, or type any food or drink in the box above.
Take care with Trimethoprim· 37
Fine with Trimethoprim· 3
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This checker summarises published guidance (NHS medicine pages, patient information leaflets and drug labels) for general information only. It is not medical advice, it is not exhaustive, and it cannot account for your dose, kidney function, other medicines, or health conditions. Always follow your prescriber, pharmacist, or the patient information leaflet — especially before changing what you eat or drink. See our editorial policy.
Further reading on Trimethoprim
The pages our answers quote. Every answer shows “Where this comes from” with the exact words, checked 24 September 2026. How we check
NHS website
About trimethoprim
NHS medicines information on trimethoprim – what it's used for and key facts.
NHS website
Who can and cannot take trimethoprim
NHS medicines information on who can take trimethoprim and who may not be able to take it.
NHS website
How and when to take trimethoprim
NHS medicines information on dosage for trimethoprim, how to take it and what to do if you miss a dose or take too much.
NHS website
Side effects of trimethoprim
NHS medicines information on side effects of trimethoprim and what you can do to cope.
NHS website
Taking trimethoprim with other medicines and herbal supplements
NHS medicines information on possible interactions with trimethoprim and other medicines, herbal remedies and supplements.
The Journal
Read our medication food guides →
A full Trimethoprim guide is on its way. Meanwhile, the Journal covers timing, grapefruit, alcohol and more.
Food groups that matter with Trimethoprim
Every medicine each one affects, on one page.