Free tool
Can I eat this with Esomeprazole?
Esomeprazole can be taken with or without food, but rich, spicy, fatty and acidic foods, caffeine and alcohol can worsen the acid symptoms it treats.
Also sold as Absizom, Nexium I.V, Ventra, Well Pharmaceuticals Heartburn and Acid Reflux Control. Brand names from the NHS Dictionary of Medicines and Devices.
Our PPIs page also covers Esomeprazole and gives one answer for the whole group. This page follows Esomeprazole’s own NHS page, so where the two differ, go by this one.
Type any food below for an instant verdict — we check 60 foods and drinks for Esomeprazole (5 to avoid, 52 to take care with) — or tap one below.
Quick answers
- Should I take Esomeprazole with food?
- Usually once a day, first thing in the morning, with or without food.
- Can I eat st john’s wort with Esomeprazole?
- No, avoid it. Do not take St John's wort with esomeprazole, as it may stop it working properly.
- Can I eat spicy food with Esomeprazole?
- Yes, with care. Try to avoid it if it seems to make your indigestion worse.
- Can I eat rich or spicy food (for feeling sick) with Esomeprazole?
- Yes, with care. If you feel sick, it may help to skip rich or spicy food.
- Can I eat tomatoes with Esomeprazole?
- Yes, with care. Acidic foods can bring on symptoms, so skip them if they affect you.
- Can I drink tea with Esomeprazole?
- Yes, with care. Try to cut down on caffeinated drinks like tea.
Grounded in the checker below. Not a substitute for your pharmacist.
1 · What do you take?
Esomeprazole can be taken with or without food, but rich, spicy, fatty and acidic foods, caffeine and alcohol can worsen the acid symptoms it treats.
You can eat and drink normally while taking esomeprazole. It's best to avoid foods that seem to make your indigestion worse, such as rich, spicy and fatty foods, and to cut down on caffeine and alcohol. Do not take St John's wort with it.
Browse our medication food guides →2 · What do you want to eat or drink?
When to take it: Usually once a day, first thing in the morning, with or without food.
Tap a food to see the answer, or type any food or drink in the box above.
Foods to avoid with Esomeprazole· 5
Take care with Esomeprazole· 52
Fine with Esomeprazole· 3
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This checker summarises published guidance (NHS medicine pages, patient information leaflets and drug labels) for general information only. It is not medical advice, it is not exhaustive, and it cannot account for your dose, kidney function, other medicines, or health conditions. Always follow your prescriber, pharmacist, or the patient information leaflet — especially before changing what you eat or drink. See our editorial policy.
Further reading on Esomeprazole
The pages our answers quote. Every answer shows “Where this comes from” with the exact words, checked 6 October 2026. How we check
NHS website
About esomeprazole
NHS medicines information on esomeprazole – what it's used for and key facts.
NHS website
Who can and cannot take esomeprazole
NHS medicines information on who can take esomeprazole and who may not be able to take it.
NHS website
How and when to take esomeprazole
NHS medicines information on dosage for esomeprazole, how to take it and what to do if you miss a dose or take too much.
NHS website
Side effects of esomeprazole
NHS medicines information on side effects of esomeprazole and what you can do to cope.
NHS website
Taking esomeprazole with other medicines and herbal supplements
NHS medicines information on possible interactions with esomeprazole and other medicines, herbal remedies and supplements.
The Journal
Read our medication food guides →
A full Esomeprazole guide is on its way. Meanwhile, the Journal covers timing, grapefruit, alcohol and more.
Food groups that matter with Esomeprazole
Every medicine each one affects, on one page.
Medicines with similar food rules
Affected by the same foods as Esomeprazole.