Free tool
Can I eat this with Methotrexate?
Methotrexate is processed by the liver (alcohol matters) and suppresses immunity (food safety matters).
Also sold as Ebetrex, Jylamvo, Methofill, Metoject PEN, Nordimet, Zlatal. Brand names from the NHS Dictionary of Medicines and Devices.
Type any food below for an instant verdict — we check 45 foods and drinks for Methotrexate (1 to avoid, 34 to take care with) — or tap one below.
Quick answers
- What foods should I eat when taking methotrexate?
- Normal, well-cooked meals are fine, and folate-rich foods like spinach, lentils, and broccoli are helpful throughout the week, but avoid alcohol, unpasteurised cheese, raw eggs from unknown sources, undercooked meat, and raw fish.
- What foods have folic acid and can I eat them with methotrexate?
- Folate-rich foods like spinach, lentils, and broccoli are safe and beneficial to eat on the same day as methotrexate — it's high-dose folic acid supplements that should be timed 24+ hours after your dose.
- Why do I need to take folic acid with methotrexate?
- Methotrexate depletes folate, so folic acid supplements (usually taken 24+ hours after your methotrexate dose) prevent side effects whilst maintaining the drug's anti-inflammatory benefits.
Grounded in the checker below and the full guide. Not a substitute for your pharmacist.
1 · What do you take?
Methotrexate is processed by the liver (alcohol matters) and suppresses immunity (food safety matters).
Keep alcohol well within NHS guidelines — your rheumatology team may advise stricter limits based on your liver results. Because immunity is reduced, follow food-safety rules you could previously shrug off. Folic acid is usually prescribed alongside — take it on the day your team specifies, not your methotrexate day.
Read our full Methotrexate guide →2 · What do you want to eat or drink?
Tap a food to see the answer, or type any food or drink in the box above.
Foods to avoid with Methotrexate· 1
Take care with Methotrexate· 34
Fine with Methotrexate· 10
Get the full methotrexate food guide by email
The complete methotrexate list — safe swaps, portion notes, and the freshness rules that matter — plus first access to the FreshPlate app, which checks every recipe against your medications automatically.
Free forever. Unsubscribe any time.
This checker summarises published guidance (NHS medicine pages, patient information leaflets and drug labels) for general information only. It is not medical advice, it is not exhaustive, and it cannot account for your dose, kidney function, other medicines, or health conditions. Always follow your prescriber, pharmacist, or the patient information leaflet — especially before changing what you eat or drink. See our editorial policy.
Further reading on Methotrexate
The pages our answers quote. Every answer shows “Where this comes from” with the exact words. How we check
Food groups that matter with Methotrexate
Every medicine each one affects, on one page.